Crystal structure of the first bromodomain of human BRD4 with benzodiazepine inhibitor
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of the first bromodomain of human BRD4 with benzodiazepine inhibitor Descriptor: 6'-(4-chlorophenyl)-1'-methyl-8'-(1-methyl-1H-pyrazol-4-yl)spiro[cyclopropane-1,4'-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine], Bromodomain-containing protein 4 Authors: Eron, S.J. Deposit date: 2020-05-07 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen-Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design. Acs Chem.Biol., 16, 2021
创建时间:
2020-05-07



