Co-crystal structure of eIF4E with nucleotide mimetic inhibitor.
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Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. Descriptor: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1 Authors: Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. Deposit date: 2015-11-04 Release date: 2016-09-07 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.61 Å) Cite: Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
创建时间：
2015-11-04
