Treg Adoptive Therapy in Subclinical Inflammation in Kidney Transplantation

NIAID Data Ecosystem2026-05-10 收录

肾癌免疫治疗

Treg细胞疗法

数据链接：

https://immport.org/shared/study/SDY2943 数据链接链接失效反馈

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资源简介：

This is a multi-center, open-label, randomized, controlled trial with 2 cohorts: 1. Maintenance CNI based immunosuppression therapy and 2. PolyTregs.

创建时间：

2025-10-30

Table6_Potential Application of Pyroptosis in Kidney Renal Clear Cell Carcinoma Immunotherapy and Targeted Therapy.XLSX

肾癌免疫治疗

细胞焦亡机制

Renal cell carcinoma (RCC) is a type of cancer with an increasing rate of morbidity and mortality and is a serious threat to human health. The treatment of RCC, especially kidney renal clear cell carc

NIAID Data Ecosystem40

DataSheet_1_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.xlsx

Treg细胞疗法

mTORC1抑制机制

Regulatory T cells (Tregs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. Nevertheless, the cl

NIAID Data Ecosystem30

RNA-seq of expanded human CRISPR/HDR-mediated FOXP3-KO naive Tregs, Cas9 naive Tregs, and conventional T cells. RNA-seq of expanded human CRISPR/HDR-mediated FOXP3-KO naive Tregs, Cas9 naive Tregs, and conventional T cells

Treg细胞疗法

CRISPRi功能基因组学

Treg cell therapy is a promising curative approach for a variety of immune-mediated conditions. CRISPR-based genome editing allows precise insertion of transgenes through homology-directed repair, but

NIAID Data Ecosystem30

RNA sequencing of CTOT19 transplantation patients [bulk RNA-seq]

肾癌免疫治疗

遗传变异分析

The CTOT19 cohort (38.2% AA, 44% White) represents a randomized controlled trial investigating the efficacy of remicade induction therapy for deceased donor kidney transplant recipients within 2 year

NIAID Data Ecosystem30

RNA-seq of expanded human CRISPR/HDR-mediated FOXP3-KO naive Tregs, Cas9 naive Tregs, and conventional T cells

Treg细胞疗法

CRISPRi功能基因组学

NIAID Data Ecosystem30