Identification of circular RNAs in response to heat stress in Chinese Holstein cows

Heat stress leads to substantial economic loss of dairy industry each year. The negative effect of heat stress in dairy cows is becoming one of the more urgent issue due to accelerating side-effects of global warming. Various genes are involved in heat stress response but the information about the role of noncoding RNAs, especially circular RNAs (circRNAs) is largely unknown. In our study, we aimed to investigate the different expression profile of circRNAs between heat stress (HS) and non-heat-stressed condition (NC) of Chinese Holstein cow's mammary gland.