Crystal structure of LY2874455 in complex of FGFR4 gatekeeper mutation (V550M)
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Crystal structure of LY2874455 in complex of FGFR4 gatekeeper mutation (V550M) Descriptor: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4 Authors: Wu, D, Chen, Y. Deposit date: 2017-04-10 Release date: 2018-08-08 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.25 Å) Cite: LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance. Chem. Commun. (Camb.), 54, 2018
创建时间：
2017-04-10
