Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex

Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex Descriptor: DNA (38-MER), MAGNESIUM ION, RNA (247-MER), ... Authors: Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. Deposit date: 2023-04-12 Release date: 2023-09-27 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis. Cell, 186, 2023