Contribution of each mutational category (transition and transversion) to the development of drug-resistant substitutions (variants) in the NS3 and NS5B proteins reported in this study.
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The genetic barrier score (GBS) was calculated according to the model described by Van de Vijver et al.(50) A score of 1 is assigned to transitions (A↔G and C↔T) and 2.5 to transversions (A↔C, A↔T, G↔C and G↔T). Natural polymorphisms are indicated in italic. Numbers of isolates are indicated in parenthesis.
创建时间:
2014-08-20



