Crystal Structures of FLAP bound to DG-031
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal Structures of FLAP bound to DG-031 Descriptor: (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, 5-lipoxygenase-activating protein, CALCIUM ION, ... Authors: Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H. Deposit date: 2020-01-07 Release date: 2020-12-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP). Biochim Biophys Acta Gen Subj, 1865, 2020
创建时间:
2020-01-07



