Mantle cell lymphoma - Female, 70 - Tissue image [5040730027993651]

This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF OTHER AND UNSPECIFIED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Generalized lymphadenopathy.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: Trepanobioptate containing bone marrow with cellularity of 70% with a population of small lymphocytes of immunophenotype: CD20(+), CD5(+), Cyclin D1(+), CD23(-), CD43(-). Within the background present CD3+ lymphocyte population and preserved cells of all hematopoietic lineages without maturation abnormalities, without CD34+ blasts, and without features of fibrosis.
The histological picture may confirm marrow involvement by mantle cell lymphoma (MCL).Sample:Material: FFPECollecting method: Surgical specimenTopography: BONES, JOINTS and ARTICULAR CARTILAGEOrgan: BONES, JOINTS AND ARTICULAR CARTILAGE OF OTHER AND UNSPECIFIED SITESTissue: IliumType of staining: positive/IHCStaining: Not applicableAntibody: CD 23Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk