Additional file 4: of Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)

Sequence comparision of Malaysian Ophiophagus hannah (MOh; current study) with Balinese species (BOh; Vonk et al. [ 20 ]) and other reported O. hannah toxins deposited in public database. First column indicates the sources of the sequence used in the comparison. Second column indicates the protein family and ID of the current study and NCBI deposited public database (Abbrev.: 3FTx, three-finger toxin; SVMP, snake venom metalloproteinase; PLA2, phospholipase A2; CRISP, cysteine-rich secretory protein; KUN, Kunitz-type proteinase inhibitor; LAAO, L-amino acid oxidase; CVF, Cobra venom factor; IGF, insulin-like growth factor; NP, natriuretic peptide; SVSP, snake venom serine protease; PDE, phosphodiesterase; NGF, nerve growth factor; AChE, acetylcholinesterase; PLB, phospholipase-B; DPP IV, dipeptidylpeptidase IV; CTL, C-type lectin; VEGF, vascular endothelial growth factor). Third column shows the accession number of NCBI and SwissProt database on the first row and (where present) the number of the line in which the peptide match is found in the protein in the subsequent rows. Forth column shows the comparison of MOh with BOh (Vonk et al. [20]) and other reported O. hannah toxins using the sequences retrieved from MOh transcriptome (current study) and NCBI database. Fifth column shows the coverage of the MOh sequences as compared to the aligned sequences. Underline indicates signal peptide sequences; green indicates peptide matches; red indicates the amino acids diverse from the aligned sequences; purple indicated sequences neither matched to O. hannah species nor BOh toxins. *Sequence comparision were based on the annotated protein ID in Addtional file 2; two filters were made for the selections: 1) every protein ID annotated to O. hannah species; 2) proteins of other snake species which are also reported in Vonk et al. [20], i.e., neurotoxin-like protein 1, belonged to [Causus rhombeatus] species but reported in BOh species. (XLSX 31 kb)