We report the effects of MazF6 overexpression on Mycobacterium tuberculosis H37Rv strain. The total RNA was isolated from M. tuberculosis harboring either pTetR-int or pTetR-Int-mazF6 the expression w
We compared global transcription in the wild type strain and a htpX (Rv0563) mutant strain. 3 seperate experiments (replicates) were performed. Overall design: Cultures were grown in 7H9 media until m
The ability of Mycobacterium tuberculosis (Mtb) to adopt heterogeneous physiological states, underlies it’s success in evading the immune system and tolerating antibiotic killing. Drug tolerant phenot