Supplementary Material for: Management of status epilepticus by different pediatric departments: neurology, intensive care and emergency medicine

Introduction: The aim of this study was to explore the differences in status epilepticus (SE) management among pediatric neurology, emergency medicine and intensive care specialists in Turkey. Methods: A 22-item questionnaire regarding first, second and third-line management strategies of SE including demographic characteristics and common etiologies according to speciality of participants was mailed to 370 specialists working in Turkey. Results: A total of 334 participants (response rate 90%); with 136 pediatric neurologists, 102 pediatric emergency medicine and 96 pediatric intensive care specialists completed the survey. While intensive care specialists frequently managed SE due to metabolic and autoimmune reasons; the most common etiologies encountered by emergency medicine specialists were epilepsy and infections. More than half of intensive care specialists (64.6%) reported using non-BDZ antiseizure medications in the 5th minute of the seizure. Most of neurologists (76.4%) preferred to administer intravenous (iv) levetiracetam infusion as a second line agent. About half of intensive care specialists and neurologists tried immunomodulatory therapies in super refractory SE. Intensive care and emergency medicine specialists were less likely to favor ketogenic diet and pyridoxine therapy for the treatment of super refractory SE. The rate of requesting EEG monitoring to recognize nonconvulsive SE was found to be very low except for neurologists. Conclusion: There was no consensus among neurologists, intensive care and emergency medicine specialists in the management of SE in Turkey. Familiarity with particular antiseizure medications and the etiologies they manage seem to be the most important factors influencing the attitudes.