An Enzymatic Approach to the Desymmetrization of Disubstituted Pyrrolines
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https://figshare.com/articles/dataset/An_Enzymatic_Approach_to_the_Desymmetrization_of_Disubstituted_Pyrrolines/3066748
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资源简介:
The enzymatic desymmetrization of 2,2- and 2,5-disubstituted
pyrroline compounds is reported in a procedure which gives
access to both enantiomers in excellent enantiomeric excess
and good yield. The enzyme reaction precursors are formed
easily from two readily available substituted pyrroles using
both ammonia (Na/NH3) and ammonia-free (Li/DBB) Birch
reduction conditions.
创建时间:
2016-03-01



