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Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients.. Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients.
Tumor-draining lymph node (TDLN) invasion by metastatic cells in breast cancer correlates with poor prognosis and is associated with local immunosuppression, which can be partly mediated by regulatory
NIAID Data Ecosystem70
ShcA is a Paracrine Integrator of the Adaptive Immune Response during Breast Cancer Progression. Mus musculus
Using transgenic mouse models of breast cancer, we demonstrate that loss of ShcA signaling within mammary tumors results in extensive CD4+ T cell infiltration, activation and induction of a humoral im
NIAID Data Ecosystem30
DataSheet_1_CD2 Is a Novel Immune-Related Prognostic Biomarker of Invasive Breast Carcinoma That Modulates the Tumor Microenvironment.csv
Female breast cancer (BCa) is the most commonly occurring cancer worldwide. The tumor microenvironment (TME) plays an essential role in tumor invasion, angiogenesis, unlimited proliferation, and even
NIAID Data Ecosystem10
DataSheet_1_A Knowledge-Based Discovery Approach Couples Artificial Neural Networks With Weight Engineering to Uncover Immune-Related Processes Underpinning Clinical Traits of Breast Cancer.zip
Immune-related processes are important in underpinning the properties of clinical traits such as prognosis and drug response in cancer. The possibility to extract knowledge learned by artificial neura
NIAID Data Ecosystem30
Single cell sequencing of CD11c-selected cells from the TME of PyMT C57BL/6N mice
We performed single-cell sequencing on CD11c-selected cells from 20 week old PyMT mice Overall design: 2 Samples
NIAID Data Ecosystem10
