BCL6 de-repression induces the fasting transcriptome and protects from steatosis (ChIP-Seq I). BCL6 de-repression induces the fasting transcriptome and protects from steatosis (ChIP-Seq I)

Here, we find that the B cell lymphoma 6 (BCL6) repressor is enriched upon feeding and converges genome-wide with PPARs to opposingly control lipid metabolism. Overall design: Identification of BCL6, PPARa, PPARd, and H3K27ac binding sites in fasted and fed livers.