Coagulation factor XI protease domain in complex with active site inhibitor
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Coagulation factor XI protease domain in complex with active site inhibitor Descriptor: 2-[2-[3-[(3~{S})-3-azanyl-2,3-dihydro-1-benzofuran-5-yl]-5-propan-2-yl-phenyl]ethoxy]-3-methoxy-benzoic acid, Coagulation factor XI, DIMETHYL SULFOXIDE, ... Authors: Renatus, M, Schiering, N. Deposit date: 2019-12-20 Release date: 2020-07-08 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.29 Å) Cite: Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J.Med.Chem., 63, 2020
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2019-12-20
