five

Mutability and hypermutation antagonize immunoglobulin codon optimality; Analysis of human MLN B cells.

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE260944
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The main objective of this study was to analyze codon optimality in relation to somatic hypermutation in natural V(D)J repertoires. Human mediastinal lymph node (10L/10R/12L/12R//2L/4R/7) B cells were sorted and analyzed by 10x Genomics 5' scRNA-seq. 5' GEX and V(D)J libraries are included.
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2025-01-23
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