RNF5-DNAJA1 Axis Dictates Selinexor Sensitivity of Multiple Myeloma by Regulating Mitochondrial Function

NIAID Data Ecosystem2026-05-02 收录

多发性骨髓瘤药物敏感性

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280576 数据链接链接失效反馈

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We performed RNA-seq to analyse the different expression genes of RNF5-KD LP-1 cells and non-target control. Examination of differentially expressed genes in RNF5-KD LP-1 cells compared with non-target control.

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2025-06-14

Correction: Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

缺氧分子机制

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Correction: Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

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Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes in MM.1S cells treated with DMSO, All-trans retinoic acid (ATRA), carfilzomib (Cfz), and their combinations. Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes in MM.1S cells treated with DMSO, All-trans retinoic acid (ATRA), carfilzomib (Cfz), and their combinations

多发性骨髓瘤药物敏感性

差异表达转录组分析

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植物逆行信号传导

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Mitochondria are crucial for plant viability and are able to communicate information on their functional status to the cellular nucleus via retrograde signalling, thereby affecting gene expression. It

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Supplement 4. Next generation sequencing results for second round screen. from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

CRISPRi筛选

多发性骨髓瘤药物敏感性

We performed secondary screening in quadruplicate and next generation sequencing was again performed in the resistant cells. Sequencing results were listed.

NIAID Data Ecosystem20

RNF5-DNAJA1 Axis Dictates Selinexor Sensitivity of Multiple Myeloma by Regulating Mitochondrial Function

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