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Combination therapy of NHS-IL12 and avelumab enhances antitumor efficacy in preclinical cancer models

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NIAID Data Ecosystem2026-03-10 收录
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Nanostring gene expression profiling of 24 BALB/c mice bearing EMT-6 tumors under avelumab and NHS-muIL12 mono and combination therapies. Six groups of four mice were profiled using samples collected on day 6. G1 is isotype control. Group 2 is 2ug NHS-muIL12. Group 3 is 10ug NHS-muIL12. Group 4 is avelumab 200ug. Group 5 is avelumab 200ug plus 2ug NHS-muIL12. Group 6 is avelumab 200ug plus 10ug NHS-muIL12.

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2018-03-21
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