N‑Amino-imidazolin-2-one Peptide Mimic Synthesis and Conformational Analysis
收藏Figshare2015-12-16 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_i_N_i_Amino_imidazolin_2_one_Peptide_Mimic_Synthesis_and_Conformational_Analysis/2020710
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Base-promoted 5-exo-dig cyclizations of aza-propargylglycinamides provided N-amino-imidazolin-2-one peptide mimics, which exhibited turn geometry in X-ray crystallographic and NMR spectroscopic analyses. Sonogashira coupling prior to cyclization afforded N-amino-imidazolin-2-ones with diverse 4-position aromatic substituents with potential to serve as Phe and Trp mimics.
创建时间：
2015-12-16
