Ketamine evoked disruption of entorhinal and hippocampal spatial maps

Companion code located at https://github.com/GiocomoLab/Masuda_et_al_2023

MEC_Neuropixels.zip
MEC spike times and behavior from acute Neuropixels insertions during a 1D VR linear track task

File names: [animal name]_[date]_baseline1_controlinjx1_ketamine1fr_corr.mat

lickt = lick timestamps, of IR beam breaks
lickx = position of animal at lick times
post = timestamps of 50 Hz VR frames
posx = position of animal at each VR frame
speed = speed of animal at each VR frame
trial = trial at each VR frame
spike_depth: depth along electrode of peak channel of each cell
all_cellCorrScore = correlation score between a trial and the baseline spatial template
all_cellStabilityScore = spatial stability for each cell on each trial
all_corrmatrix = firing correlation of each cell between each pair of trials
all_drugEffectScores = [ketamine FR diff, control FR diff, ketamine FR effect score, ketamine corr effect score, spike depth] for each cell
       FR effect score = the ratio ketamine vs control of the differences between the avg FR of the pre-injection trials and the the avg FR of the equivalent number of trials post-injection
corr effect score = difference between the average of the corrScore in the 25 trials before ketamine and the average of the corrScore in the 25 trials after ketamine appication
all_fr = mean firing rate per cell per trial per spatial bin
all_fr_smoothed = save as all_fr, smoothed with Gaussian kernel
all_frTime = firing rate of each cell averaged over each VR frame
all_peakiness = mean crest factor of each cell
all_spatialinfo = mean spatial information of each cell
all_spatialInfoCurve = spatial information of each cell on each trial
all_spike_idx = spike times for each cell, in VR bins
all_waveforms = waveforms of each cell
avg_all_cellCorrScore = avarge cellCorrScores curves for each trial
avg_all_corrmatrix = trial by trial correlation for all cells
avg_all_fr: mean firing rate per position bin per trial over all cells
avg_cell_fr: mean firing rate over full session per cell

CA1_miniscope.zip
CA1 calcium transients from 1-photon imaging during a freely moving context exploration

Folder names: M[mouse number][F for female, nothing for male]

behavIndividualsf.mat
neuronIndivisualsf.mat
sessions.mat
thresh.mat