Mean (95% confidence interval) test class performance of regression and machine learning models for predicting the infecting DENV serotype using all titre predictor variables (Scenario A).

For each performance metric, the mean and 95% confidence interval were calculated using 100 bootstrap samples of the hold-out-sample (10%). There were no DENV4 cases in the test set. ANN: artificial neural network. MLR: multinomial logistic regression. SVM: support vector machine. GBM: gradient boosting machine. RF: random forest. PRNT: plaque reduction neutralisation test. DENV: dengue virus. JEV: Japanese encephalitis virus. PPV: positive predictive value. NPV: negative predictive value.