Morphometric analysis of rat hearts (therapy-study).

Morphometric data of rat hearts harvested at the end of the therapy-study were obtained by computer-aided analysis of H&E-stained mid-ventricular 2 μm cross-sections as previously described in detail [18]. Parameters given are (from top to bottom, mean ±SEM): LVAtot, total LV-area; LVCA, LV-cavity area; LVWA, LV wall area (including LVCA/LVWA-ratio in %); IVS, thickness of the inter-ventricular septum; PW, posterior wall thickness (one way ANOVA and Dunnett`s post-hoc test Treated vs. control *p<0.05 †p<0.01 ‡p<0.001. Morphometric analysis of rat hearts (therapy-study).