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Genome-wide maps of macroH2A and H2B distribution in murine embryonic fibroblasts in dependence of Lsh.

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https://www.ncbi.nlm.nih.gov/sra/SRP237758
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资源简介:
We report here the distribution of the histone variant macroH2A in murine embryonic fibroblasts derived fom Lsh-/- embryos or Lsh+/+ embryos day 14 gestation using ChIP-seq analysis. We find that macroH2A1 and macroH2A2 deposition are reduced in the absence of Lsh in contrast to H2B deposition. The study identifies Lsh as important regulator of genome wide macroH2A deposition. Overall design: Examination of 2 different histone modifications in 2 cell types.
创建时间:
2020-11-13
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