A genome-wide RNAi screen for T. brucei MMS damage response factors
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
To identify genome maintenance pathways active in a divergent eukaryote and important parasite, Trypanosoma brucei, we performed RNAi screens to search for genes important for survival following exposure to the alkylating agent methyl methanesulphonate. Amongst a cohort of broadly conserved and, therefore, early evolved T. brucei repair pathways, we reveal novel Trypanosoma- or kinetoplastid-specific repair-associated activities.
创建时间：
2021-02-04
