p53 mutation is common and highly related to radiotherapy resistance in rectal cancer. APR-246, as a small molecule, can restore the tumor-suppressor function to mutant p53. There is no study on combi
In this project, we established an intratumoral iteration model of colorectal cancer radiotherapy resistance, designated as IR-MC38, and compared its tumor microenvironment to that of the parental MC3
p53 mutation is common and highly related to radiotherapy resistance in rectal cancer. APR-246, as a small molecule, can restore the tumor-suppressor function to mutant p53. There is no study on combi