BACH1 alters the expression of EMT-related genes to promote metastasis in pancreatic cancer

NIAID Data Ecosystem2026-05-02 收录

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EMT上皮间充质转化

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124408 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-07-31

DataSheet_1_MYCT1 Inhibits the Adhesion and Migration of Laryngeal Cancer Cells Potentially Through Repressing Collagen VI.xlsx

癌症转移机制

细胞粘附

MYCT1, a target of c-Myc, inhibits laryngeal cancer cell migration, but the underlying mechanism remains unclear. In the study, we detected differentially expressed genes (DEGs) from laryngeal cancer

NIAID Data Ecosystem50

Migration speed of captured breast cancer subpopulations correlates with metastatic fitness. Migration speed of captured breast cancer subpopulations correlates with metastatic fitness

癌症转移机制

细胞迁移动力学

The genetic alterations contributing to migration proficiency, a phenotypic hallmark of metastatic cells required for colonizing distant organs, remain poorly defined. Here, we used single-cell magnet

NIAID Data Ecosystem40

shRNAi profiling of human MDA-MB-231 cells expressing anti-p53 (shp53) short-hairpin RNAs treated with TFGbeta or control

癌症转移机制

转录组功能分析

TGFβ ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers. The molecular nature of this switch remains enigmatic.

NIAID Data Ecosystem30

Additional file 2 of An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes

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多组学整合分析

Additional file 2. Gene set characterization. Gene set characterization of the DE genes between early and late stages. The downregulated genes are significantly enriched for cancer-related gene signat

NIAID Data Ecosystem50

NFIC1 suppresses migration and invasion of breast cancer cells through interferon-mediated Jak-STAT pathway

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Jak-STAT信号通路

NFIC1, the longest isoform of NFIC, is essential for the regulation on spatiotemporal expressions of drug-metabolizing genes in liver. However, the role of NFIC1 in breast cancer is not clear. Here we

NIAID Data Ecosystem40

BACH1 alters the expression of EMT-related genes to promote metastasis in pancreatic cancer

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