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Parasite strain-specific pathogenesis in murine infections with Trypanosoma brucei

ChEBI2010-03-03 更新2026-07-21 收录

锥虫致病机制

寄生虫株特异性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-17049 数据链接链接失效反馈

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资源简介：

Parasite strain-specific pathogenesis in murine infections with Trypanosoma brucei

应用场景：

创建时间：

2010-03-03

蛋白质法尼基化

锥虫致病机制

Kinesins are a family of motor proteins conserved throughout eukaryotes. In our present study we characterize a novel kinesin, KinesinCaaX, orthologs of which are only found in the kinetoplastids and

NIAID Data Ecosystem60

Determinants of GPI-PLC Localisation to the Flagellum and Access to GPI-Anchored Substrates in Trypanosomes

锥虫致病机制

外膜蛋白调控

In Trypanosoma brucei, glycosylphosphatidylinositol phospholipase C (GPI-PLC) is a virulence factor that releases variant surface glycoprotein (VSG) from dying cells. In live cells, GPI-PLC is localis

NIAID Data Ecosystem60

Table_1_Cerebrospinal Fluid-Derived Microvesicles From Sleeping Sickness Patients Alter Protein Expression in Human Astrocytes.XLSX

锥虫致病机制

脑脊液分析

Human African trypanosomiasis (HAT) caused by the extracellular protozoon Trypanosoma brucei, is a neglected tropical disease affecting the poorest communities in sub-Saharan Africa. HAT progresses fr

NIAID Data Ecosystem40

TbCMT1

锥虫致病机制

毒力相关基因

The mRNA cap methyltransferase gene TbCMT1 is redundant in vitro but a virulence factor in vivo for bloodstream form Trypanosoma brucei.

NIAID Data Ecosystem60

Genomes of two new Trypanosoma brucei isolates. Genomes of two new Trypanosoma brucei isolates

寄生虫基因组学

锥虫致病机制

Two lines of Trypanosoma brucei were isolated from cattle in Uganda. The DNA is from parasites that had undergone two rodent passages.

NIAID Data Ecosystem40