Human renin in complex with compound 5
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Human renin in complex with compound 5 Descriptor: (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-[(1R,2S,3S,5S,7S)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]hexanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin Authors: Takahashi, M, Matsui, Y, Hanzawa, H. Deposit date: 2012-06-26 Release date: 2013-05-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor. Acs Med.Chem.Lett., 3, 2012
创建时间：
2012-06-26
