Crystal structure of human BACE-1 bound to Compound 6
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Crystal structure of human BACE-1 bound to Compound 6 Descriptor: (4S)-4-(2,4-difluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... Authors: Vajdos, F.F, Parris, K. Deposit date: 2014-11-26 Release date: 2015-03-04 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design. J.Med.Chem., 58, 2015
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2014-11-26
