This file contains the source data for Extended Data Figure 1c. c, Hi-C matrix (at 5 kb resolution) and loops at the MRR1 region showing two looping silencers (S1 and S2) that exhibit chromatin intera
To gain insight into the history of islet cell deterioration along the progression from normal glycemic regulation to T2D, we collected surgical pancreatic tissue samples from 133 metabolically phenot
Background/Aims: Insulin-secreting islet β-cells adapt to the insulin resistance associated with pregnancy by increasing functional β-cell mass, but the placental signals involved in thi
