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资源简介：
CD3d SCID Patient cells and Jurkat Disease Models Edited with ABE editors
应用场景：
创建时间：
2022-12-22
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Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
Measurement of base substitution induced by adenine base editor
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Ex vivo therapeutic base and prime editing using chemically derived hepatic progenitors in a mouse model of tyrosinemia type 1. Kim et al.
Bipotent differentiation capacity of HT1-mCdHs. (A) Gene expression levels of mature hepatocyte-specific markers determined by RT-qPCR. Gapdh was used as an internal control. Data are mean ± SD (n=9).
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WGS for source cell lines, MC38, CT26, AT3 and EMT6
Whole genome sequence for source cell lines for murine tumor models from two genetic backgrounds, C57BL/6J (B6) and BALB/cJ (BALB), covering both mammary gland and colon cancers: MC38 (colon; B6), CT2
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Precise correction of heterozygous SHOX2 mutations in hiPSCs derived from patients with atrial fibrillation via genome editing and sib-selection
Patient-specific human induced pluripotent stem cells (hiPSCs) offer unprecedented opportunities for the investigation of multigenic disease, personalized medicine, and stem cell therapy. For heteroge
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In vivo Ryr2 editing corrects catecholaminergic polymorphic ventricular tachycardia
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal inherited arrhythmia disorder most commonly caused by missense mutations in the RyR2 gene. The goal of this study was to determ
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