Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control
The log (p-value) of each pathway was determined using Fisher’s exact test. The ratios were calculated as the number of input molecules mapped to a specific pathway divided by the total number of mole
The goal of this collaborative, interdisciplinary project is to develop powerful, generalizable approaches for discovering how risk variants for psychiatric disorders shape neurobiological processes a