Bcl11b
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资源简介：
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including T cell differentiation; epithelial cell development; and neuron differentiation. Located in neuron projection and nucleus. Part of SWI/SNF complex. Is expressed in several structures, including alimentary system; central nervous system; cranium; nose; and skin. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BCL11 transcription factor B). [provided by Alliance of Genome Resources, Nov 2024]
此数据集旨在促进DNA结合转录激活剂活性，特异性地作用于RNA聚合酶II及其顺式调控区序列的DNA结合活性。该活性在上游或多个过程中发挥作用，包括T细胞分化、上皮细胞发育和神经元分化。该蛋白定位于神经元突起和细胞核内，并构成SWI/SNF复合体的一部分。其在多个结构中表达，包括消化系统、中枢神经系统、颅骨、鼻腔和皮肤。该基因的人类同源基因与免疫缺陷49有关，与人类BCL11B（BCL11转录因子B）同源。[由基因组资源联盟提供，2024年11月]
提供机构：
Rat Genome Database
