NG Capture-C analysis of GADD45a-bound adipogenic super-enhancers
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE99606
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资源简介：
ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We previously found that ING1b is essential to target GADD45a-mediated active DNA-demethylation via TET1 to specific loci. In order to study the physical interaction of distant GADD45a and ING1 bound regions, we performed multiplexed NG Capture-C chromatin conformation capture assay in wildtype and knockout mouse embryonic fibroblasts. NG Capture-C analysis of multiple GADD45a-bound adipogenic super-enhancers in wildtype, Gadd45a knockout, Ing1 knockout and Gadd45a/Ing1 double-knockout (DKO) mouse embryonic fibroblasts.
创建时间：
2021-07-25
