five

Human PRMT5:MEP50 structure with Fragment 3 and MTA Bound

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Protein Data Bank Japan2023-10-25 更新2026-04-19 收录
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Human PRMT5:MEP50 structure with Fragment 3 and MTA Bound Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, 7-chloro-1-methyl-1H-benzimidazol-2-amine, Methylosome protein 50, ... Authors: Gunn, R.J, Lawson, J.D, Smith, C.R. Deposit date: 2022-05-13 Release date: 2022-10-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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2022-05-13
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