Cdc45

INVOLVED IN DNA unwinding involved in DNA replication (ortholog); ASSOCIATED WITH androgen insensitivity syndrome (ortholog); Androgen Insensitivity Syndrome due to Coactivator Deficiency (ortholog); autism spectrum disorder (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); CMG complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil

参与DNA解旋过程，涉及DNA复制（同源基因）；与雄激素不敏感综合征（同源基因）相关；由共活化剂缺乏引起的雄激素不敏感综合征（同源基因）；自闭症谱系障碍（同源基因）；存在于中心粒（同源基因）、纤毛基体（同源基因）、CMG复合物（同源基因）；与1-萘基异硫氰酸酯、2,3,7,8-四氯二苯并-对-二氧杂芑、6-丙基-2-硫基尿嘧啶相互作用。