Transcriptomic profiling of human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CMs) and cardiac progentiors (hiPSC-CPs) from tetralogy of Fallot (TOF) patients with DiGeorge Syndrome (DG) and without DiGeorge Syndrome (ND)

DG accounts for most of the identifiable cases of TOF. Exploring and comparing the transcriptome of hiPSC-CMs and hiPSC-CPs from TOF-DG and TOF-ND could provide a bettering understanding on TOF. Day 7,8 and 11 hiPSC-CPs undergoing in vitro cardiac differentiation derived from 2 control-, 1 TOF-DG- and 1 TOF-ND-hiPSC lines. Day22 hiPSC-CMs (fabricated into cardiac anisotropic sheets, CAS) derived from 2 control-, 2 TOF-DG- and 2 TOF-ND-hiPSC lines.