Molecular characterization of an operon required for pertussis toxin secretion.
收藏PubMed Central1993-04-01 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC46218/
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资源简介：
Mutants of Bordetella pertussis which are defective in secretion of pertussis toxin were isolated and characterized. The region of the B. pertussis chromosome identified by mutagenesis as playing a role in transport of pertussis toxin was sequenced. Analysis of this region revealed eight open reading frames, seven of which predict a protein exhibiting homology with one of the VirB proteins of Agrobacterium tumefaciens, which are involved in the transport of the T-DNA molecule across bacterial and plant membranes. Thus a set of accessory proteins are most likely involved in the secretion of pertussis toxin, and these proteins appear to be members of a family of proteins involved in the secretion of macromolecules from bacteria.
提供机构：
National Academy of Sciences
创建时间：
1993-04-01
