Correlations of <i>in vitro</i> IC's values between the different drugs tested in 46 field isolates as well as associations between the IC's values and the major polymorphisms in <i>pfmdr1</i> and <i>pfmrp1</i> genes.

§Cells show P-value (2-tailed) and in brackets the Pearson correlation coefficient between the IC's values of the different antimalarial tested in the isolates. P value<0.05 is considered significant (2-tailed). ¤Cells show P-value (2-tailed) of the linear association analysis between the main polymorphisms found in the isolates (Table 2) and the in vitro drug IC's values. Isolates that harbors both alleles (mixed infection) in the determined polymorphic region were excluded from the statistical analysis. T-test with equal variances assumed was used to test differences. Bold numbers are considered significant for T-test (P<0.05). For comparison, Bonferroni-adjusted levels of significance would be: P value<0.0042. ART: artemisinin, DHA: dihydroartemisinin, MQ: mefloquine, LUM: lumefantrine, IC50 and IC90: Inhibition Concentration of 50% and 90%. CNV: copy number variation.