Dynamic range compression (DRC) by hexapeptide libraries increases MS/MS-based identification of lower-abundance proteins in complex mixtures. However, two unanswered questions impede fully realizing

NIAID Data Ecosystem60

Proline hydroxylation of ChREBP

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代谢转录调控

This project investigated proline hydroxylation of ChREBP. Proline hydroxylation was investigated in flag-IP enriched protein extracts from ChREBP-flag overexpressing HEK293 cells (A) and in ChREBP-IP

NIAID Data Ecosystem50

A method to distinguish between lysine acetylation and lysine ubiquitination with feature selection and analysis

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特征选择

Lysine acetylation and ubiquitination are two primary post-translational modifications (PTMs) in most eukaryotic proteins. Lysine residues are targets for both types of PTMs, resulting in different ce

DataCite Commons2024-03-24 更新70

TAILS N-Terminomics and Proteomics Show Complex Regulation of Proteolytic Processing by O-glycosylation

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糖基化-蛋白水解调控

Proteolytic processing is an irreversible post-translational modification functioning as a ubiquitous regulator of cellular activity. Protease activity is tightly regulated by control of gene expressi

NIAID Data Ecosystem50

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