Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis. Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis

In this study, we performed whole transcriptomics analysis (RNA-seq) in a cohort of colorectal polyps and the matched normal tissue in FAP patients, which reveals a significant activation of inflammatory and cell proliferation pathways. Overall design: RNA-seq data to identify potential FAP preventive targets by comparing paired colorectal adenomas (TA) to adjacent normal colonic mucosa (UM) from FAP patients.