Investigating_early_host_intestinal_epithelial_cells___whipworm_interactions. Investigating_early_host_intestinal_epithelial_cells___whipworm_interactions

Whipworms (Trichuris trichiura) are soil-transmitted helminths and the etiologic agent of the human disease, trichuriasis. Whipworms live preferentially in the cecum of their hosts where they tunnel through epithelial cells and cause inflammation potentially resulting in colitis. Despite extensive research, the role of early whipworm interactions with host intestinal epithelial cells in triggering parasite establishment remains unclear. Here, we investigate novel interactions of whipworms with the host intestinal epithelia during the early stages of infection. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/