Structure of full length LRRK2 bound to GZD-824 (I2020T mutant)
收藏Protein Data Bank Japan2023-12-27 更新2026-04-19 收录
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Structure of full length LRRK2 bound to GZD-824 (I2020T mutant) Descriptor: 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ... Authors: Villagran-Suarez, A, Sanz-Murillo, M, Alegrio-Louro, J, Leschziner, A. Deposit date: 2023-08-26 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Sci Adv, 9, 2023
创建时间：
2023-08-26
