HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.
收藏官方服务：
资源简介：
HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.
应用场景：
创建时间：
2013-02-12
相关数据集
MicroRNA profiling of Basal ganglia tissue from chronically SIV infected rhesus macaques II
The study describes miRNA expression changes in basal ganglia (BG) of chronically SIV-infected rhesus macaques. HIV/SIV-associated neurological disorder (HAND) represents a major comorbidity affecting
NIAID Data Ecosystem40
Modeling HIV-1 Induced Neuroinflammation in Mice: Role of Platelets in Mediating Blood-Brain Barrier Dysfunction
The number of HIV-1 positive individuals developing some form of HIV-associated neurocognitive disorder (HAND) is increasing. In these individuals, the integrity of the blood-brain barrier (BBB) is co
NIAID Data Ecosystem30
HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway
Diminished adult neurogenesis is considered a potential mechanism in the pathogenesis of HIV-1-associated dementia (HAD). In HAD, HIV-1-infected and immune-activated brain mononuclear phagocytes (MP;
NIAID Data Ecosystem10
CCR5 controls neuronal damage in an in vivo model of HIV glycoprotein 120-induced brain injury. Mus musculus
The chemokine receptor CCR5 is a major co-receptor for human immunodeficiency virus 1 (HIV-1) mediating infection of target cells1,2. Beyond its function as co-receptor, CCR5 also influences the cours
NIAID Data Ecosystem40
Data_Sheet_1_Reversal of Cognitive Impairment in gp120 Transgenic Mice by the Removal of the p75 Neurotrophin Receptor.PDF
Activation of the p75 neurotrophin receptor (p75NTR), by the proneurotrophin brain-derived neurotrophic factor (proBDNF), triggers loss of synapses and promotes neuronal death. These pathological feat
NIAID Data Ecosystem20
