首页/数据集/Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

ChEBI2012-02-26 更新2026-07-21 收录

增强子功能分析

高通量基因调控筛选

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31982 数据链接链接失效反馈

官方服务：

资源简介：

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

应用场景：

创建时间：

2012-02-26

发育调控

增强子功能分析

The NK homeodomain factor Tinman is a crucial regulator of early mesoderm patterning and, together with the GATA factor Pannier and the Dorsocross T-box factors, serves as one of the key cardiogenic f

NIAID Data Ecosystem60

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors

干细胞转录调控

增强子功能分析

Stem cells are a central feature of metazoan biology. Haematopoietic stem cells (HSCs) represent the best-characterized example of this phenomenon, but the molecular mechanisms responsible for their f

PubMed Central2002-06-17 更新50

Enhancers with tissue-specific activity are enriched in intronic regions. Enhancers with tissue-specific activity are enriched in intronic regions

增强子功能分析

神经分化表观遗传学

We have performed ChIP-seq of H3K27ac and H3K4me3 histone post-translational modifications at three stages during induced neural differentiation (ESCs, neural progenitors and neurons). This data has a

NIAID Data Ecosystem30

Enhancers predominantly control transcription initiation. Enhancers predominantly control transcription initiation

基因表达调控

增强子功能分析

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem60

The interdependency between MiDAC complex and MLL3/4 complexes

表观遗传调控

增强子功能分析

Enhancers play a pivotal role in gene transcriptional regulation in response to developmental cues. Active enhancers are marked by H3K4me1/2 and H3K27ac, while poised enhancers are marked by H3K27me3

NIAID Data Ecosystem40

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

资源简介：

相关数据集