Lipid loci with multiple signals in East Asians.
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aLD (r2/D′) with SNP showing the strongest evidence of association at each locus.bβ: effect size from an additive model and corresponding to the effect allele, in the unit of mmol/L for HDL-C, LDL-C and natural log transformed TG.cP values of sequential conditional analyses, in which we added the SNP with the strongest evidence of association into the regression model as a covariate and tested for the next strongest SNP until the strongest SNP showed a conditional P value>10−4 and had no annotation suggesting potential function.dVariance explained by SNPs at each locus was estimated based on CLHNS samples (n = 1,716).eP values of initial association in African Americans and Europeans.
创建时间:
2015-12-02



