Data underlying the chapter: Introduction to oxidoreductases in chiral amine synthesis

This dataset contains data collected during experiments at Delft University of Technology, as a chapter of the dissertation written by Ewald Jongkind. The aim of this work was to introduce the state of the art on chiral amine synthesis, with emphasis on enzymes from the oxidoreductase class. This was done by collecting reported IRED, RedAm and EneIRED sequences and comparing the active site residues. Dataset consists of a comparison of different reported IREDs, RedAms, and EneIREDs by sequence alignment and a phylogenetic tree, visualized in Excel and PowerPoint. More information can be found in the README-file.

本数据集源自埃瓦尔德·容金德（Ewald Jongkind）学位论文的其中一章，数据采集自代尔夫特理工大学（Delft University of Technology）开展的相关实验。本研究旨在系统介绍手性胺合成领域的研究现状，重点关注氧化还原酶（oxidoreductase）类酶。研究通过搜集已公开报道的IRED、RedAm及EneIRED序列，并比对其活性位点残基来实现上述目标。本数据集包含经序列比对与系统发育树（phylogenetic tree）分析得到的不同已报道IRED、RedAm及EneIRED的对比结果，相关可视化工作通过Excel与PowerPoint完成。更多详细信息可查阅README文件。