In-depth proteomic analysis of nasal fluids from patients with chronic rhinosinusitis and nasal polyps by data-independent acqusition

Antibiotics are commonly prescribed to treat chronic rhinosinusitis (CRS). However, the effects of antibiotics on the microbiome and secreted proteome remain unknown in regard to CRS.We analyzed the effects of antibiotics on the nasal secreted proteome inthe context of CRS using data-independent acqusition proteomics approach.