Exosomes from MSC facilitate diabetic wound healing by promoting angiogenesis

Mesenchymal stem cell (MSC)-derived exosomes had been reported to be a prospective candidate in accelerating diabetic wound healing. Hence, this study intended to explore whether exosomes originating from the human umbilical cord MSC (hucMSC) could display a superior proangiogenic effect on diabetic wound repair and its underlying molecular mechanism. Overall design: The conditioned medium of MSCs was collected to isolate Exos.